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Pharmacies & Drug Stores in the US - Market Research Report (2016-2031)

Marley Brocker Marley Brocker New York, United States Last Updated: February 2026 NAICS 44611

Revenue

$693.9bn

2026

$693.9bn

Past 5-Year Growth

Profit

$XX.Xbn

Employees

1m

Businesses

53,228

Wages

$XX.Xbn

Pharmacies & Drug Stores in the US industry analysis

Pharmacies and drug stores remain central to US healthcare delivery, with revenue steadily growing despite periods of moderate volatility in recent years. The industry has benefited from a growing and aging population, as older adults require ongoing medication to manage chronic conditions—leading to higher prescription refill volumes. At the same time, expanded access to private insurance and public programs like Medicare and Medicaid is giving more people insurance coverage and supporting demand for brand-name prescriptions, which are the largest product segment for pharmacies. Steady introductions of new specialty medicines—over 50 specialty drugs received FDA approval in 2025—and the popularity of high-demand therapies such as GLP-1 agonists have also contributed to rising prescription spending. These trends together have supported robust revenue growth at an estimated CAGR of 2.7% to $693.9 billion by the end of 2026, including 3.5% growth in 2026 alone.

Trends and Insights

  • Vertical integration is increasingly concentrating prescription volume among fewer companies. Large chains link retail pharmacies with insurers and PBMs to direct patient flow. This structure makes it more difficult for smaller pharmacies to compete and retain prescriptions.
  • Brand-name prescriptions generate the most revenue. Because patents protect these drugs, they often come with higher prices, making them more expensive than generics and ensuring they remain the most significant revenue source for pharmacies.
  • Pharmacies take advantage of proximity to key downstream healthcare-related businesses. Stores benefit from being near hospitals, nursing homes or healthcare complexes because it reduces customer travel times.
  • Retail pharmacies are expanding healthcare services to diversify their revenue streams. In-store clinics, vaccinations and chronic care programs help major chains reduce reliance on low-margin prescriptions while increasing customer retention and visit frequency.
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Industry Statistics and Trends

Market size and recent performance (2016-2031)

Industry revenue has grown at a CAGR of 2.7 % over the past five years, to reach an estimated $693.9bn in 2026.

Trends and Insights

Rite Aid's closure underscores broader struggles facing retail pharmacies

  • Rite Aid filed for bankruptcy twice in under two years, with the second filing in May 2025, as it struggled with billions of dollars in debt and opioid-related lawsuits. After closing hundreds of locations during restructuring, the chain ultimately shuttered all remaining stores by fall 2025, ending more than six decades in business. Most of the remaining pharmacy files were sold to competitors, including CVS, Walgreens and Kroger, which absorbed prescription volume across over a thousand locations.
  • Additional trends and insights available with purchase
Pharmacies & Drug Stores in the US
Revenue (2016-2031)
IBISWorld Logo Source: IBISWorld

Industry outlook (2026-2031)

Market size is projected to grow over the next five years.

Trends and Insights

Improving macroeconomic conditions and demographic shifts benefit pharmacies

  • Many pharmacies and drug stores will continue to expand their services to include preventive care options and additional front-end offerings. Consumers appreciate the added convenience, and some are willing to pay a higher price for the ability to buy medications, consumer care goods and grocery items in the same location.

Biggest companies in the Pharmacies & Drug Stores in the US

Company
Market Share (%)
2026
Revenue ($m)
2026
Profit ($m)
2026
Profit Margin (%)
2026
Cvs Health Corporation
129,890.7
3,124.8
2.4
Walgreens Boots Alliance, Inc.
121,476.2
-1,086.1
-0.9
Walmart Inc.
59,723.8
2,718.3
4.6

To view the market share and analysis for all 5 top companies in this industry, view purchase options.

Products & Services Segmentation

Pharmacies & Drug Stores in the US
Products & Services
IBISWorld Logo Source: IBISWorld

Industry revenue is measured across several distinct product and services lines, including Branded prescription drugs , Generic drugs and Nonprescription medicines . Branded prescription drugs is the largest segment of the Pharmacies & Drug Stores in the US.

Trends and Insights

Patent cliffs and biosimilar competition threaten branded drug sales

  • Definition Branded prescription drugs are patented medications sold under manufacturer trademarks at premium prices. These include specialty therapies for chronic and complex conditions such as oncology, immunology, diabetes (for example, GLP-1 agonists like Ozempic), cardiovascular disease and rare disorders. Branded drugs dominate pharmacy revenue because of the limited availability of generic substitutes, high list prices and favorable reimbursement structures that prioritize them on drug formularies.
  • More insights available in the full report

Table of Contents

About this industry

Industry definition

Pharmacies and drug stores retail a range of prescription and over-the-counter medications, health and beauty items, toiletries and consumable goods directly to consumers on a walk-in basis. Industry companies may also provide basic health and photo-processing services. The industry excludes mail-order retailers, hospitals and clinics.

What's included in this industry?

Products and services covered in the Pharmacies & Drug Stores industry in the United States include Branded prescription drugs, Generic drugs, Nonprescription medicines, Personal health supplies, Groceries and food items, Vitamins, minerals and dietary supplements and Cosmetics.

Companies

Companies covered in the Pharmacies & Drug Stores industry in the United States include Cvs Health Corporation, Walgreens Boots Alliance, Inc. and Walmart Inc.

Purchase this report to view all 5 major companies in this industry.

Related Terms

Related terms covered in the Pharmacies & Drug Stores industry in the United States include over-the-counter (otc) medications, prescription drug, blockbuster drug, formulary, front-end sales and pharmacy benefit manager (pbm).

Industry Code

NAICS 2017

NAICS 44611 - Pharmacies & Drug Stores in the US

Performance

Get an indication of the industry's health through historical, current and forward-looking trends in the performance indicators that make or break businesses.

Analyst insights

Vertical integration is increasingly concentrating prescription volume among fewer companies. Large chains link retail pharmacies with insurers and PBMs to direct patient flo...

In this chapter (4)

  • Current Performance
  • Outlook
  • Volatility
  • Life Cycle

Key metrics

  • Annual Revenue, Recent Growth, Forecast, Revenue Volatility
  • Number of Employees, Recent Growth, Forecast, Employees per Business, Revenue per Employee
  • Number of Businesses, Recent Growth, Forecast, Employees per Business, Revenue per Business
  • Total Profit, Profit Margin, Profit per Business

Charts

  • Revenue, including historical (2016-2025) and forecast (2026-2031)
  • Employees, including historical (2016-2025) and forecast (2026-2031)
  • Businesses, including historical (2016-2025) and forecast (2026-2031)
  • Profit, including historical (2016-2026)
  • Industry Volatility vs. Revenue Growth
  • Industry Life Cycle

Detailed analysis

  • Trends in supply, demand and current events that are driving current industry performance
  • Expected trends, economic factors and ongoing events that drive the industry's outlook
  • Key success factors for businesses to overcome volatility
  • How contribution to GDP, industry saturation, innovation, consolidation, and technology and systems influence the industry's life cycle phase.

Products and Markets

Learn about an industry's products and services, markets and trends in international trade.

Analyst insight

Brand-name prescriptions generate the most revenue. Because patents protect these drugs, they often come with higher prices, making them more expensive than generics and ensu...

In this chapter

  • Products & Services
  • Major Markets

Key metrics

  • Largest market segment and value in 2026
  • Product innovation level

Charts

  • Products & services segmentation in 2026
  • Major market segmentation in 2026

Detailed analysis

  • Trends impacting the recent performance of the industry's various segments
  • Innovations in the industry's product or service offering, specialization or delivery method
  • Key factors that successful businesses consider in their offerings
  • Buying segments and key trends influencing demand for industry products and services

Geographic Breakdown

Discover where business activity is most concentrated in an industry and the factors driving these trends to find opportunities and conduct regional benchmarking.

Analyst insights

Pharmacies take advantage of proximity to key downstream healthcare-related businesses. Stores benefit from being near hospitals, nursing homes or healthcare complexes becaus...

In this chapter (1)

  • Business Locations

Charts

  • Share of revenue, establishment, wages and employment in each state
  • Share of population compared to establishments in each region in 2026

Tables

  • Number and share of establishments in each state in 2026
  • Number and share of revenue each state accounts for in 2026
  • Number and share of wages each state accounts for in 2026
  • Number and share of employees in each state in 2026

Detailed analysis

  • Geographic spread of the industry across North America, and trends associated with changes in the business landscape
  • Key success factors for businesses to use location to their advantage

Competitive Forces

Get data and insights on what's driving competition in an industry and the challenges industry operators and new entrants may face, with analysis built around Porter's Five Forces framework.

Analyst insights

Retail pharmacies are expanding healthcare services to diversify their revenue streams. In-store clinics, vaccinations and chronic care programs help major chains reduce reli...

In this chapter (4)

  • Concentration
  • Barriers to Entry
  • Substitutes
  • Buyer & Supplier Analysis

Key metrics

  • Industry concentration level
  • Industry competition level and trend
  • Barriers to entry level and trend
  • Substitutes level and trend
  • Buyer power level and trend
  • Supplier power level and trend

Charts

  • Market share concentration among the top 4 suppliers from 2021-2026
  • Supply chain including upstream supplying industries and downstream buying industries, flow chart

Detailed analysis

  • Factors impacting the industry’s level of concentration, such as business distribution, new entrants, or merger and acquisition activity.
  • Key success factors for businesses to manage the competitive environment of the industry.
  • Challenges that potential industry entrants face such as legal, start-up costs, differentiation, labor/capital intensity and capital expenses.
  • Key success factors for potential entrants to overcome barriers to entry.
  • Competitive threats from potential substitutes for the industry’s own products and services.
  • Key success factors for how successful businesses can compete with substitutes.
  • Advantages that buyers have to keep favorable purchasing conditions.
  • Advantages that suppliers have to maintain favorable selling conditions.
  • Key success factors for how businesses can navigate buyer and supplier power.

Companies

Learn about the performance of the top companies in the industry.

Analyst insights

Large national chains dominate the US pharmacy landscape. Companies like CVS Health, Walgreens and Walmart account for a substantial share of prescriptions through expansive ...

In this chapter

  • Market Share Concentration
  • Companies
  • Company Spotlights

Charts

  • Industry market share by company in 2022 through 2026
  • Major companies in the industry, including market share, revenue, profit and profit margin in 2026
  • Overview of Cvs Health Corporation's performance by revenue, market share and profit margin from 2020 through 2026
  • Overview of Walgreens Boots Alliance, Inc.'s performance by revenue, market share and profit margin from 2020 through 2026
  • Overview of Walmart Inc.'s performance by revenue, market share and profit margin from 2020 through 2026
  • Overview of revenue, market share and profit margin trend for 2 additional companies

Detailed analysis

  • Description and key data for Cvs Health Corporation, and factors influencing its performance in the industry
  • Description and key data for Walgreens Boots Alliance, Inc., and factors influencing its performance in the industry
  • Description and key data for Walmart Inc., and factors influencing its performance in the industry
  • Description, key data and performance trends for 2 additional companies

External Environment

Understand the demographic, economic and regulatory factors that shape how businesses in an industry perform.   

Analyst insights

The rising population aged 65 and older has driven up prescription volumes in recent years. Older adults typically require multiple ongoing medications. This trend has increa...

In this chapter

  • External Drivers
  • Regulation & Policy
  • Assistance

Key metrics

  • Regulation & policy level and trend
  • Assistance level and trend

Charts

  • Regulation & Policy historical data and forecast (2016-2031) 
  • Assistance historical data and forecast (2016-2031) 

Detailed analysis

  • Demographic and macroeconomic factors influencing the industry, including Regulation & Policy and Assistance
  • Major types of regulations, regulatory bodies, industry standards or specific regulations impacting requirements for industry operators
  • Key governmental and non-governmental groups or policies that may provide some relief for industry operators.

Financial Benchmarks

View average costs for industry operators and compare financial data against an industry's financial benchmarks over time. 

Analyst insights

The prevalence of low-priced generic drugs has cut into industry profitability. Consumers recognize the benefits of using generic drugs to keep costs low while granting them ...

In this chapter

  • Cost Structure
  • Financial Ratios
  • Key Ratios

Key metrics

  • Profit margin, and how it compares to the sector-wide margin
  • Average wages, and how it compares to the sector-wide average wage
  • Largest cost component as a percentage of revenue
  • Industry average ratios for days' receivables, industry coverage and debt-to-net-worth ratio

Charts

  • Average industry operating costs as a share of revenue, including purchases, wages, depreciation, utilities, rent, other costs and profit in 2026
  • Average sector operating costs as a share of revenue, including purchases, wages, depreciation, utilities, rent, other costs and profit in 2026
  • Investment vs. share of economy

Data tables

  • Industry Multiples (2019-2024)
  • Industry Tax Structure (2019-2024)
  • Income Statement (2019-2024)
  • Balance Sheet (2019-2024)
  • Liquidity Ratios (2019-2024)
  • Coverage Ratios (2019-2024)
  • Leverage Ratios  (2019-2024)
  • Operating Ratios (2019-2024)
  • Cash Flow & Debt Service Ratios (2016-2031)
  • Revenue per Employee (2016-2031)
  • Revenue per Enterprise (2016-2031)
  • Employees per Establishment (2016-2031)
  • Employees per Enterprise (2016-2031)
  • Average Wage (2016-2031)
  • Wages/Revenue (2016-2031)
  • Establishments per Enterprise (2016-2031)
  • IVA/Revenue (2016-2031)
  • Imports/Demand (2016-2031)
  • Exports/Revenue (2016-2031)

Detailed analysis

  • Trends in the cost component for industry operators and their impact on industry costs and profitability 

Key Statistics

Industry Data

Data Tables

Including values and annual change:

  • Revenue (2016-2031)
  • IVA (2016-2031)
  • Establishments (2016-2031)
  • Enterprises (2016-2031)
  • Employment (2016-2031)
  • Exports (2016-2031)
  • Imports (2016-2031)
  • Wages (2016-2031)

Top Questions Answered

Unlock comprehensive answers and precise data upon purchase. View purchase options.

What is the market size of the Pharmacies & Drug Stores industry in the United States in 2026?

The market size of the Pharmacies & Drug Stores industry in the United States is $693.9bn in 2026.

How many businesses are there in the Pharmacies & Drug Stores industry in the United States in 2026?

There are 53,228 businesses in the Pharmacies & Drug Stores industry in the United States, which has grown at a CAGR of 4.7 % between 2021 and 2026.

How may import tariffs affect the Pharmacies & Drug Stores industry in the United States?

The Pharmacies & Drug Stores industry in the United States is unlikely to be materially impacted by import tariffs with imports accounting for a low share of industry revenue.

How may export tariffs affect the Pharmacies & Drug Stores industry in the United States?

The Pharmacies & Drug Stores industry in the United States is unlikely to be materially impacted by export tariffs with exports accounting for a low share of industry revenue.

Has the Pharmacies & Drug Stores industry in the United States grown or declined over the past 5 years?

The market size of the Pharmacies & Drug Stores industry in the United States has been growing at a CAGR of 2.7 % between 2021 and 2026.

What is the forecast growth of the Pharmacies & Drug Stores industry in the United States over the next 5 years?

Over the next five years, the Pharmacies & Drug Stores industry in the United States is expected to grow.

What are the biggest companies in the Pharmacies & Drug Stores industry in the United States?

The biggest companies operating in the Pharmacies & Drug Stores industry in the United States are Cvs Health Corporation, Walgreens Boots Alliance, Inc. and Walmart Inc.

What does the Pharmacies & Drug Stores industry in the United States include?

Branded prescription drugs and Generic drugs are part of the Pharmacies & Drug Stores industry in the United States.

Which companies have the highest market share in the Pharmacies & Drug Stores industry in the United States?

The company holding the most market share in the Pharmacies & Drug Stores industry in the United States is Cvs Health Corporation.

How competitive is the Pharmacies & Drug Stores industry in the United States?

The level of competition is high and increasing in the Pharmacies & Drug Stores industry in the United States.

Methodology

How are IBISWorld reports created?

IBISWorld has been a leading provider of trusted industry research for over 50 years to the most successful companies worldwide. With offices in Australia, the United States, the United Kingdom, Germany and China, we are proud to have local teams of analysts that conduct research, data analysis and forecasting to produce data-driven industry reports.

Our analysts start with official, verified and publicly available sources of data to build the most accurate picture of each industry. Analysts then leverage their expertise and knowledge of the local markets to synthesize trends into digestible content for IBISWorld readers. Finally, each report is reviewed by one of IBISWorld’s editors, who provide quality assurance to ensure accuracy and readability.

IBISWorld relies on human-verified data and human-written analysis to compile each standard industry report. We do not use generative AI tools to write insights, although members can choose to leverage AI-based tools within the platform to generate additional analysis formats.

What data sources do IBISWorld analysts use?

Each industry report incorporates data and research from government databases, industry-specific sources, industry contacts, and our own proprietary database of statistics and analysis to provide balanced, independent and accurate insights.

Key data sources in the US include: 

  • US Census Bureau
  • US Bureau of Labor Statistics
  • US International Trade Commission

Analysts also use industry specific sources to complement catch-all sources, although their perspective may focus on a particular organization or representative body, rather than a clear overview of all industry operations. However, when balanced against other perspectives, industry-specific sources provide insights into industry trends.

These sources include:

  • Industry and trade associations
  • Industry federations or regulators
  • Major industry players annual or quarterly filings

Finally, IBISWorld’s global data scientists maintain a proprietary database of macroeconomic and demand drivers, which our analysts use to help inform industry data and trends. They also maintain a database of statistics and analysis on thousands of industries, which has been built over our more than 50-year history and offers comprehensive insights into long-term trends.

How does IBISWorld forecast its data?

IBISWorld’s analysts and data scientists use the sources above to create forecasts for our proprietary datasets and industry statistics. Depending on the dataset, they may use regression analysis, multivariate analysis, time-series analysis or exponential smoothing techniques to project future data for the industry or driver. Additionally, analysts will leverage their local knowledge of industry operating and regulatory conditions to impart their best judgment on the forecast model.

IBISWorld prides itself on being a trusted, independent source of data, with over 50 years of experience building and maintaining rich datasets and forecasting tools. We are proud to be the keystone source of industry information for thousands of companies across the world.

Learn more about our methodology and data sourcing on the Help Center.

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